People age differently

In a study published in PNAS titled "Quantification of Biological ageing in young adults", scientist have found that several biomarkers to detect ageing and show that people age at different rates.


What does it mean:
This is very significant finding and explain what is generally observed in daily lives that some people of the same age group look younger while others look very old. This is not limited to just the skin or hairs but extends to the age of the organs as well.

We all must have heard about people who were very young but suddenly passed away due to a disease which was not even life threatening. Now we know some answers although the study was not mechanistic (explaining the mechanism (or how it occurs)), it is a very important finding.

The study and main Findings:
954 young humans enrolled in what is called the Dunedin Study birth cohort, tracking multiple biomarkers across three time points spanning their third and fourth decades of life.
 This depends on quantification of the pace of coordinated physiological deterioration across multiple organ systems (e.g., pulmonary, periodontal, cardiovascular, renal, hepatic, and immune function).

They found that young individuals of the same chronological age varied in their “biological aging” (declining integrity of multiple organ systems). Already, before midlife, individuals who were aging more rapidly were less physically able, showed cognitive decline and brain aging, Self reported worse health, and looked older. Measured biological aging in young adults can be used to identify causes of aging and evaluate rejuvenation therapies.

Read the original article at:
http://www.pnas.org/content/early/2015/07/01/1506264112.abstract

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